Intelligent Retinol™

Key Benefits Visibly Smoother, Brighter Skin Retinol gently exfoliates to visibly smooth and brighten the complexion over time. Supercharged Yet Gentle Results Enhanced with climbazole and Time-Release technology for increased and lasting retinol power that's slowly released throughout the night to remain gentle on skin. Lightweight Nourishment Infused with squalane and vitamin E for effective yet lightweight moisturisation that leaves skin feeling soft and supple. Firmer-Looking Complexion Works to improve both the look and feel of skin firmness. Customise Your Routine With 3 Progressive Strengths Available in a choice of 3TR (0.3% retinol), 6TR (0.6% retinol) and 10TR (1% retinol) so you can build up your visible results over time. How to Use First-time use If you're new to Intelligent Retinol, we recommend a patch test at least 24 hours before first use. Learn how to patch test here . Phase in application gradually. Use twice a week for the first 2 weeks, every other night for the next 2 weeks, then every night. Step 1 After cleansing in the evening, massage 4 drops across the face, neck and décolletage. Step 2 Allow to absorb then follow with a moisturiser. We recommend Advanced Night Restore which is specifically designed to be used after vitamin A. Uses per bottle 100 Guide to Layering Step 1: Cleanse Surface Radiance Cleanse™ Select a Size Full Size (150ml) Full Size (150ml) Travel Size (40ml) Add to Bag £25 Step 2: Renew Intelligent Retinol™ Select a Size Intelligent Retinol 3TR™ Intelligent Retinol 3TR™ Intelligent Retinol 6TR™ Intelligent Retinol 10TR™ Add to Bag £39 Step 3: Target Liquid Peptides™ Select a Size Full Size (30ml) Full Size (30ml) Travel Size (8ml) Add to Bag £59 Step 4: Moisturise Advanced Night Restore™ Select a Size Full Size (50ml) Full Size (50ml) Travel Size (12.5ml) Add to Bag £62 Key Ingredients Retinol This classic form of vitamin A helps to support collagen levels and enhance the skin’s natural renewal cycle. This promotes a smoother and more youthful-looking complexion. Climbazole Climbazole has been proven to boost the activity of vitamin A in the skin, for increased age-defying power without the common irritating effects. Squalane An almost skin-identical lipid which helps to support the natural skin barrier by nourishing the complexion. Vitamin E A powerful antioxidant that helps to protect against the ageing effects of free radicals. It also helps to boost the power of retinol for optimum visible results. Squalane An almost skin-identical lipid which helps to support the natural skin barrier by nourishing the complexion. Vitamin E A powerful antioxidant that helps to protect against the ageing effects of free radicals. It also helps to boost the power of retinol for optimum visible results. See More View all No artificial fragrance No synthetic colours Paraben free Alcohol free Certified by the vegan society Experts Recommended "This is age-defying retinol with a performance-enhancing twist." DANIEL ISAACS Chief Product Officer "If pigmentation and fine lines are your biggest bugbear." CLARE STEPHENSON Beauty Writer - Red Can I use Intelligent Retinol while pregnant or breastfeeding? As a cosmetics company, we are unable to provide product advice in relation to medical conditions such as pregnancy or breastfeeding. We strongly recommend discussing the ingredients with your GP or midwife before use. We do, however, generally recommend avoiding vitamin A use while pregnant or breastfeeding. When and how should I apply Intelligent Retinol? Intelligent Retinol should only be applied as part of your evening regime. After cleansing in the evening, massage 4 drops evenly across face, neck and décolletage. Follow with a moisturiser. Can I use Intelligent Retinol Eye TR alongside vitamin C formulas? Absolutely. In fact we recommend it as part of our pioneering CSA Philosophy which champions vitamin C plus sunscreen by day, vitamin A by night as the simple secret to glowing, youthful-looking skin. What's the difference between Intelligent Retinol and Crystal Retinal? The main difference is that Intelligent Retinol is formulated with retin OL , whereas Crystal Retinal is formulated with next-generation retin AL . While retinol is a great option for vitamin A beginners, retinal is proven to work up to 11x faster than standard retinol in delivering visible age-defying results.* *G. Seigenthaler et al., Biochemical Journal, 1990, 268, pp 371-378. Help Products About Resources Svetlana Y. 🇩🇪 Verified Buyer 10/01/26 Toma A. 🇬🇧 Verified Buyer 03/12/25 Amber S. 🇺🇸 Verified Buyer 15/08/25 Oksana B. 🇬🇧 Verified Buyer 02/07/25 Sarah L. 🇬🇧 Verified Buyer 02/10/26 Olha M. 🇺🇦 Verified Buyer 16/09/26 Shop Medik8’s Intelligent Retinol facial serum with squalane, available in 0.3–1% retinol strengths to smooth fine lines, even skin tone, and boost radiance. Discover visibly youthful, smooth and bright skin with Intelligent Retinol. This performance-enhanced vitamin A serum is expertly infused with climbazole (a proven retinol booster), for maximum visible age-defying results. Add to that nourishing squalane, Medik8's unique Time Release technology, and a choice of 3 progressive strengths for youth-boosting power that remains gentle on all skin types. Please Note: Product packaging shown may be different to the product received due to regional variations